Prescription Pattern of Proton Pump Inhibitors at Hospital Admission and Discharge

Nutritional assessment in hospitalized patients of orthopedic ward at hospital admission and discharge time in Shohadaye Ashayer hospital

Background: Malnutrition is one of the significant factors in extending hospitalization period, augmenting disease complications, enhancing treatment and hospitalization costs, and increasing deaths in hospitals. This study was conducted to investigate patients, nutritional conditions, before and discharge time in the orthopedic ward of Shohadaye Ashayer hospital in 2010. Materials and Methods...

Proton Pump Inhibitors: Omeprazole

Oral Proton Pump Inhibitors

There is currently a lack of evidence to suggest superior clinical efficacy of one oral proton pump inhibitor over any other. Proton pump inhibitors display similar doseresponse relationships with similar potencies and efficacies at the equivalent dose. The decision to select one proton pump inhibitor over another is likely to be based on the agents’ licensed indication, patient tolerability an...

Intravenous proton pump inhibitors.

Intravenous (IV) administration of a proton pump inhibitor (PPI) is a faster way to achieve gastric acid suppression than oral administration of the same agent. Peak suppression after IV administration occurs within hours, compared with several days later after oral administration. Thus the IV route of administration offers a faster onset of gastric suppression, achievement of intragastric pH c...

Proton Pump Inhibitors and Gastritis

Proton pump inhibitors (PPIs) are novel compounds that strongly inhibit the H(+)/K(+)-ATPase in the gastric parietal cells to cause profound suppression of acid secretion. Acid-generating ATPase, also known as vacuolar-type ATPase, is located in the lysozomes of leukocytes and osteoclasts and its activity is also reportedly influenced by treatment with PPIs. This concept is supported by the res...